Introduction to mutations

Today started our notes on mutations.  A key misunderstanding with the term "mutation" is that it means "Bad" or "Freakish".  Not all mutations turn you in to 
Frankenstein..... I PROMISE you that!!! 
 The daily questions gave you a look into the different 
effects mutations can have.

Using your codon chart – translate the following mRNA sequence

AUG CCA UAC CGC CGG UUU

   Met – Pro – Tyr – Arg – Arg - Phe

What would happen if the following letter changed?

AUG CCG UAC CGC CGG UUU

Met – Pro – Tyr- Arg – Arg – Phe

 The amino acid sequence remained the same – “Silent” mutation.

AUG CCA UAC CGC CAG UUU

Met – Pro – Tyr – Arg – Gin – Phe

“Missense” mutation

AUG CCA UAG CGC CGG UUU

Met – Pro - STOP

“NonSense” mutation

We then started into the notes about mutations.  We will continue with these tomorrow!!  Check Edline for the notes.