Thursday, January 31, 2013

When Mitosis goes wrong


Today we started with the following daily questions
Thursday January 31st
What do you think would happen if a cell moved right into the Synthesis phase without making sure that G1 correctly occurred?
To answer this you needed to look and see what happens during the G1 phase.  During G1 the cell is growing and building more organelles.  If the cell just flew through to the S-phase there could be the chance that the cell had not grown large enough or built enough organelles to continue with the cell cycle.

What would happen if the cell did not properly go through the S phase and moved into G2 then mitosis?
For this questions we need to look at what is happening during the S phase.  During the S phase DNA is being replicated.  If the cell did not make sure that happened properly the cell may not have made a full copy of the DNA or the newly replicated DNA may be damaged and that will the be passed on to the daughter cell.

The Eukaryotic cell cycle takes MUCH longer than the prokaryotic cell cycle.  What are TWO reasons this may be?
Let's think about the differences between eukaryotic and prokaryotic cells.  The MAIN difference between eukaryotic and prokaryotic cells is the presence of a nucleus in eukaryotic cells.  Therefore, eukaryotic cells must perform mitosis and prokaryotic cells do not.  A second reason is that Eukaryotic cells have a LOT more DNA than prokaryotic cells and DNA replication would take much longer.
The goal of these daily questions was to get you minds to start thinking about when the cell cycle DOESN'T go as planned.  We will be talking about cell cycle controls and cancer next.  To introduce this though, I let you watch the following National Geographic clips about real life giants.  We will be seeing that signals sent from different cells determine how often cells divide.  In people with gigantism or acromegaly to much growth hormone is being released which acts as a signal for cells to continue to divide.


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